Skip to main content
Christopher R. Mueller PhD
 Christopher R. Mueller
Contact Info

Faculty Bio

Transcription factors in cancer Stress and Breast Cancer BRCA1 and Stem Cells Liquid Biopsy Circulating Tumour DNA

Selected Publications

Heather Ritter and Christopher R Mueller. Expression microarray identifies the unliganded glucocorticoid receptor as a regulator of gene expression in mammary epithelial cells. BMC Cancer. 2014 Aug 5; (14)275: 8807-8814

Kirsten Nesset, Ami Perri and Christopher R Mueller. The Glucocorticoid Receptor Gene Expression is Reduced and its Promoter is Hypermethylated in a Significant Percentage of Breast Tumours. Epigenetics. 2014 Jun 1;9(6): 851-859.

Lixin Zhou, Marcia Graves, Gwen Macdonald, Jane Cipollone, Christopher R Mueller and Calvin  Roskelley. Microenvironmental regulation of BRCA1 gene expression by c-Jun and Fra2 in pre-malignant human ovarian surface epithelial cells.  Molecular Cancer Research. 2013 Mar;11(3):272-81

 Heather Ritter, Lilia Antonova and Christopher Mueller. The unliganded glucocorticoid receptor positively regulates the tumour suppressor BRCA1 through GABP beta . Molecular Cancer Research 2012 Apr;10(4):558-69.

Crista Thompson, Gwen MacDonald and Christopher R Mueller.  Decreased expression of BRCA1 in SK-BR-3 cells is the result of  aberrant activation of the GABP Beta promoter by an NRF-1 containing complex.  Molecular Cancer. 2011 May 24;10:62.

Lilia Antonova,  Kristan Aronson and Christopher Mueller. Stress and Breast Cancer:  From Epidemiology to Molecular Biology.  Breast Cancer Res. 2011 Apr 21;13(2):208

Lilia Antonova and Christopher R Mueller. Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: a possible molecular link between stress and breast cancer. Genes Chromosomes Cancer. 2008;47:341-352.

Gwen MacDonald, Melissa Stramwasser and Christopher R Mueller. Characterization of a negative transcriptional element in the BRCA1 promoter. Breast Cancer Res. 2007;9:R49