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Seminar Series




Wednesday April 5th, 2023

1:00pm – 2:00pm

School of Medicine, Room 123A

Dr. Avena C. Ross

Associate Professor

Department of Chemistry

Queen’s University

Investigating the biosynthesis of tambjamines: bacterial alkaloid natural products

Natural Products are molecules produced by living organisms that serve as a means of communication and competition with other organisms. The innate bioactivities of Natural Products have been leveraged for the development of many drug therapies particularly for the treatment of infectious diseases and cancers. The prodiginines and tambjamines comprise a large family of microbially produced bioactive alkaloid Natural Products. They are characterized by a common bipyrrole and subclassified as prodiginines when they contain a third pyrrole or tambjamines with an alkyl amine instead. Despite isolation of a sizeable number of tambjamine molecules from natural sources, only a very small number of these molecules have been correlated with a producing microbe and a biosynthetic gene cluster, thereby limiting our understanding of the biosynthesis of the tambjamine subclass. In this presentation, the genome-guided isolation of several tambjamines will be discussed alongside our work on the biosynthesis of these alkaloids and investigations of several enzymatic steps in the later stages of prodiginine and tambjamine production.


BMED 897 MSc Seminars

Tuesday January 31, 2023

1:00 pm – 2:00 pm

Botterell Hall, Room B139


Richard Nauman

Microbes, Immunity and Inflammation Field

1:00 – 1:30 pm

Investigating the Role of Trained Immunity in Bladder Cancer Progression                

Supervisor – Dr. Charles Graham


Julia Barilo

Microbes, Immunity and Inflammation Field

1:30 – 2:00 pm

Characterizing the Innate Immune Response of Alternatively Activated Macrophages to LCMV Infection                      

Supervisor – Dr. Sam Basta



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BMED 897 MSc Seminars

Daniella Gilmour

Experimental Medicine Field

Supervisor – Drs. Alan Lomax and Stephen Vanner

Synergistic Effects of Histamine and Proteases in Visceral Hypersensitivity

Tuesday January 24, 2023

1:00 pm – 2:00 pm

Botterell Hall, Room B139



BMED 897 Student Symposium


Tuesday April 04, 2023

12:30 pm – 2:25 pm                                                        

Botterell Hall, Room B139




Seminar Title



12:30  pm

Jayne Dent              BCB

Functional Testing of Chromosome-19 microRNA Cluster (C19MC) in Metastatic Skin Cutaneous Melanoma

Andrew Craig

12:45 pm

Jocelyn Lee              BCB

Probing Structure-Function Relationships of an                Ice Nucleation Protein Using a Droplet Freezing Assay

Peter Davies

1:00 pm

Dylan Falconer          BCB

Biosynthesis of Bacterial Polysaccharides

Inka Brockhausen Chris Lohans

1:15 pm

Leila Tibouti              BCB

Characterizing the Functional Implications of Polyhistidine Polyphosphorylation in Transcription Factors

Zongchao Jia

1:30 pm


10 Minute Break


1:40 pm

Lauren Brown           TDDHT

Investigating the Impact of Valproic Acid on           Placental Development in CD-1 Mice

Louise Winn

1:55 pm

James Cornwell         EM

Investigating the Novel Role of hERG as an                    ITIM-Containing Fcy Receptor

Shetuan Zhang


2:10 pm

Sahil Sachdev           EM

The Role of Microbial Metabolites in the               Regulation of Satiety Signalling


Alan Lomax

David Reed



Seminar Attendance & Rubric Evaluations Submission